Schedule

Day 1

09:30 - 09:50

Registration

Tea, coffee and poster set up.

09:50 - 10:00

Welcome and opening remarks

To be given by Andrew Chalmers and Carly Dix.

Session 1

Chair: Chair-Alison Banham, University of Oxford, UK

Sponsored by GeneTex

10:00 - 10:30

Mathias Uhlén, Royal Institute of Technology (KTH), Sweden

Enhanced validation of antibodies for research applications

10:30 - 11:00

Birte Aggeler, Bio-Techne/R&D Systems, USA

Antibody Validation: New Tools, scientific thinking and common sense

11:00 - 11:30

Break

Tea, coffee, posters and sponsors' exhibition.

Session 2

Chair: Christopher Pudney, University of Bath, UK

11:30 - 12:00

Kathryn Lilley, University of Cambridge, UK

Probing the spatial proteome

12:00 - 12:30

Deepa Shankar, Thermo Fisher Scientific, USA.

Nailing it with Thermo Fisher Scientific’s antibody validation toolbox!

Lunch

12:30 - 13:15

Lunch

13:15 - 14:00

Poster exhibition.

*poster presenters please stand by your poster

Session 3

Chair: Fridtof Lund-Johansen, Oslo University Hospital, Norway

14:00 - 14:30

Richard Goodwin, AstraZeneca, UK

Imaging mass cytometry and multimodal mass spectrometry imaging combined to define drug delivery, metabolism and response

14:30 - 15:00

Alejandra Solache, Abcam, UK

Title TBC

15:00 - 15:30

Break

Tea, coffee, posters and sponsors' exhibition.

Session 4

Chair: Arthur Lewis, MedImmune, UK

15:30 - 16:00

Jan Roger, GSK, UK

The approaches GSK are using to ensure antibodies are fit for purpose for target identification/validation.

16:00 - 16:30

Jason Li, Proteintech, USA

The role of antigens in antibody validation

Discussion forum

Chair: James Hunt, AstraZeneca, UK.

Sponsored by GeneTex

16:30 - 18:00

Part 1: What can suppliers do to improve antibody validation?

The panel will include: Birte Aggeler (Bio-Techne/R&D Systems), Deepa Shankar (Thermo Fisher Scientific), Alejandra Solache (Abcam), Roberto Polakiewicz (Cell Signaling Technology), Jason Li (Proteintech), Karin Abarca Heidemann (Rockland Immunochemicals).

Part 2: What can end users do to improve antibody validation?

The panel will include: Mathias Uhlen (Royal Institute of Technology KTH), Alison Banham (University of Oxford), Stephen Hearty (Immunocore), Karine Enesa (AstraZeneca), Dagmar Ernhofer (BioMed X) and Fridtof Lund-Johansen Oslo University Hospital (TBC).

All delegates will be invited to ask questions and join in the discussion.

19:30 - late

Conference social event.

The evening starts at 7.30pm with a meal at Brasserie Blanc in central Bath. If you haven"t booked yet but would still like to come, please drop us an email

Day 2

08:30 - 09:00

Open

Tea, coffee and poster set up.

Session 5

Chair: Stephen Hearty, Immunocore, UK

09:00 - 09:30

Roberto Polakiewicz, Cell Signaling Technology, USA

The science behind antibody validation at Cell Signaling Technology.

09:30 - 09:50

Fridtjof Lund-Johansen, Oslo University Hospital, Norway.

Array-based antibody validation

09:50 - 10:20

Dagmar Ehrnhoefer, BioMed X, Germany.

Validation of post-translational modification specific antibodies for non-histone proteins

10:20 - 10:50

Break

Tea, coffee, posters and sponsors' exhibition

Session 6

Chair: Carly Dix, AstraZeneca, UK

10:50 - 11:10

Peter Kloehn, MRC Prion Unit at UCL, UK.

Identifying antibodies against cryptic antigens on the ectodomain of cancer targets

11:10 - 11:40

Gemma Jones, Astra Zeneca, UK.

Validation of clinical IHC biomarker assays for translational science.

11:40 - 11:50

Closing remarks

To be given by Andrew Chalmers and Carly Dix