Schedule

Day 1

Tuesday the 9th of September 2025

13:00 - 15:00

Registration

Tea, coffee and poster set up.

15:00 - 15:15

Welcome and opening remarks

To be given by Andrew Chalmers & Carly Dix.

Session 1

Chair: Andrew Chalmers, CiteAb, UK

15:15 - 15:35

Ulf Landegren, Uppsala University, SE

Minimizing antibody cross-reactivity and revealing dynamic protein activity states via dual recognition in solution and in situ.

15:35 - 15:55

Amy Turner, Proteintech, UK

Epitope-Mapped Recombinant Antibodies: A New Standard in Antibody Validation.

15:55 - 16:10

Stefan Schuechner, Medical University of Vienna, AT

Protein Phosphatase 2A carboxy terminus: how insufficient validation of post-translational modification specific antibodies misled the field for over 20 years.

16:10 - 16:30

Carly Dix, AstraZeneca, UK

Overcoming Antibody Selection, Validation, and Generation Challenges to Accelerate the Discovery of New Medicines.

16:30 - 18:00

Drinks reception

Day 2

Wednesday the 10th of September 2025

09:00 - 09:30

Open

Tea, coffee and pastries

Session 2

Chair: Alejandra Solache, Abcam, UK

09:30 - 09:50

Andrew Bradbury, Specifica, an IQVIA business, US

The AIntibody challenge: an update on the use of AI/ML in antibody discovery.

09:50 - 10:10

Will Howat, Abcam, UK

Antibody Quality is not just about specificity.

10:10 - 10:30

Libby Wiseman, AstraZeneca, UK

The impact of pre-analytical factors on immunohistochemistry assays that detect labile Phospho-epitopes.

10:30 - 11:00

Break

Tea, coffee, posters and sponsors' exhibition

Session 3

Chair: Asel Sartbaeva, University of Bath, UK

11:00 - 11:20

Johan Duchêne, Ludwig Maximilian University of Munich, DE

The DARC Side of Antibodies.

11:20 - 11:40

Nidhi Nath, Bio-Techne, US

Antibody Development and Validation in the Era of Spatial Proteomics.

11:40 - 12:00

Myriam Duckely, Novartis, CH

Tool antibodies in early drug discovery.

12:00 - 13:15

Lunch

Lunch, posters and sponsors' exhibition

Session 4 (short talks)

13:15 - 13:30

Elisia Clark, The Michael J. Fox Foundation, US

Research Resources for Tool Validation through the Michael J. Fox Foundation.

13:30 - 13:45

Ruth McAdam, GlaxoSmithKline, UK

A view from Pharma: Custom antibody sourcing at GSK.

13:45 - 14:00

Jim Trimmer, University of California, Davis, US

Open-Source Antibodies as a Path to Enhanced Research Reproducibility and Transparency.

14:00 - 14:15

Jonathan Schmid-Burgk, University of Bonn, DE

Pooled validation screening and affinity maturation of AI-designed protein binders.

14:15 - 14:30

Björn Forsström, Olink Proteomics, SE

Expanding validation of Proximity Extension Assays.

14:30 - 16:00

Poster session

Tea, coffee, posters and sponsors' exhibition

Session 5

Chair: Katarzyna Kmiecik, Alchemab Therapeutics, UK

16:00 - 16:20

Deborah Moshinsky, Institute for Protein Innovation (IPI), US

Systematic Antibody Validation for Community Distribution Using High-Throughput Biophysical and Functional Testing.

16:20 - 16:40

Roberto Polakiewicz, Cell Signaling Technology, US

Antibody validation in the age of spatial and single cell biology.

16:40 - 17:00

Andrew Buchanan, Stealth Mode Biotech, UK

19:30 - late

Conference dinner

Conference social event (Hilton, Bath)

Day 3

Thursday the 11th of September 2025

09:00 - 09:30

Open

Tea, coffee and pastries

Session 6

Chair: Elena Ivanova, Regeneron, US

09:30 - 09:50

Michael Weiner, Precision BioTools, US

MILKSHAKE and Sundae: Sweet Solutions to the Bitter Problem of anti-PTM Specific Antibody Validation.

09:50 - 10:10

Leticia Montoya, Thermo Fisher Scientific, US

Accelerating spatial proteomics research with Thermo Fisher Scientific's specificity verified antibodies.

10:10 - 10:30

Carl Laflamme, Neuro-SGC, YCharOS initiative, CA

Antibody Validation as a Scientific Discipline: Lessons and Challenges from YCharOS.

10:30 - 10:45

Zoé Butti, New York Genome Center, US

Mapping the Cellular Landscape of Protein Aggregation Across ALS, FTD, and Alzheimer's Disease.

10:45 - 11:15

Break

Tea, coffee, posters and sponsors' exhibition

Session 7

Chair: Carly Dix, AstraZeneca, UK

11:15 - 11:35

Elena Ivanova, Regeneron, US

What does a scientist need to select an IHC antibody?

11:35 - 11:55

Thierry Le Bihan, Rapid Novor, CA

One Clone to Rule Them All: Turning pAbs into rAbs.

11:55 - 12:15

Andrea Radtke, Leica Microsystems, US

It takes a community: Impact of HuBMAP and grassroots efforts to characterize antibodies for spatial biology applications.

Closing remarks

To be given by Andrew Chalmers & Carly Dix